Find hotels in Big Pine Key, FL from $111

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Compare 2,540 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Old Wooden Bridge Resort and Marina

2.5 star property
8.6 out of 10, Excellent, (225)
"Very nice and quiet! "
The price is $256
includes taxes & fees
$239 per night
May 4 - May 5
Old Wooden Bridge Resort and Marina

Barnacle Resort

3.0 star property
8.2 out of 10, Very Good, (34)
"The staff was great! But the gem of the property is the seclusion with the amazing view of the ocean…Absolutely stunning! Loved it…Would stay there again!"
The price is $295
includes taxes & fees
$262 per night
May 13 - May 14
Barnacle Resort

Gulf View Waterfront Resort

2.5 star property
8.6 out of 10, Excellent, (455)
"Nice quiet place to stay for your home base of Marathon."
The price is $161
includes taxes & fees
$143 per night
May 4 - May 5
Gulf View Waterfront Resort

Grassy Flats Resort & Beach Club

2.5 star property
9.4 out of 10, Exceptional, (274)
"very nice resort with good food, drinks and surroundings"
The price is $449
includes taxes & fees
$399 per night
May 20 - May 21
Grassy Flats Resort & Beach Club

Rainbow Bend Resort

2.5 star property
8.2 out of 10, Very Good, (622)
"The rooms are very nice, and very clean"
The price is $172
includes taxes & fees
$153 per night
May 5 - May 6
Rainbow Bend Resort

Glunz Ocean Beach Hotel & Resort

3.0 star property
9.0 out of 10, Wonderful, (1001)
"One of our favorite places in the Keys!"
The price is $233
includes taxes & fees
$207 per night
Jun 1 - Jun 2
Glunz Ocean Beach Hotel & Resort

Floating Sea Cove Resort & Marina

2.0 star property
4.8 out of 10, (1000)
"Very clean, attention to detail, quiet Staff was very helpful "
The price is $111
includes taxes & fees
$99 per night
May 26 - May 27
Floating Sea Cove Resort & Marina

Hampton Inn Marathon - Florida Keys

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Good stay and good breakfast options."
The price is $202
includes taxes & fees
$180 per night
May 15 - May 16
Hampton Inn Marathon - Florida Keys

Fairfield Inn & Suites by Marriott Marathon Florida Keys

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Beautiful area and very clean hotel. We loved our stay!"
The price is $196
includes taxes & fees
$174 per night
May 26 - May 27
Fairfield Inn & Suites by Marriott Marathon Florida Keys

Bonefish Bay Motel

2.5 star property
9.2 out of 10, Wonderful, (395)
"beautiful spot to stay loved our stay"
The price is $158
includes taxes & fees
$141 per night
May 13 - May 14
Bonefish Bay Motel

Seascape Resort & Marina

3.0 star property
9.4 out of 10, Exceptional, (510)
"Nice place to stay when visiting the Keys"
The price is $239
includes taxes & fees
$212 per night
May 7 - May 8
Seascape Resort & Marina

Siesta Motel

2.0 star property
7.4 out of 10, Good, (634)
"It was a nice stay, comfy "
The price is $152
includes taxes & fees
$135 per night
May 8 - May 9
Siesta Motel

Aqua Lodge Rentals At Coconut Cay

3.5 star property
9.6 out of 10, Exceptional, (159)
"Truly enjoyed our time in such a unique experience. "
The price is $347
includes taxes & fees
$322 per night
May 12 - May 13
Aqua Lodge Rentals At Coconut Cay

Coconut Cay Resort & Marina

2.0 star property
8.4 out of 10, Very Good, (1002)
"Nice place, will definitely stay again if in the area."
The price is $176
includes taxes & fees
$157 per night
May 14 - May 15
Coconut Cay Resort & Marina

Kingsail Resort

2.0 star property
8.4 out of 10, Very Good, (1005)
"Great stay!"
The price is $148
includes taxes & fees
$132 per night
May 5 - May 6
Kingsail Resort

Tropical Cottages

3.0 star property
8.4 out of 10, Very Good, (805)
"It was verry cozy!"
The price is $135
includes taxes & fees
$120 per night
May 5 - May 6
Tropical Cottages

Yacht Haven Marina

3.5 star property
9.8 out of 10, Exceptional, (139)
"Perfect location, plenty of attractions close by. "
The price is $293
includes taxes & fees
$274 per night
May 4 - May 5
Yacht Haven Marina

Skipjack Resort & Marina

3.0 star property
8.6 out of 10, Excellent, (1180)
"Mid way thru the Keys was a plus. It's off season, but everything was very good, and we see that they are working to make the experience even better for the busy season. We'd definitely stay again!"
Skipjack Resort & Marina

Aqua Lodges at 47th Street Gulfside

3.0 star property
8.2 out of 10, Very Good, (33)
"The view is incredible "
The price is $286
includes taxes & fees
$254 per night
May 5 - May 6
Aqua Lodges at 47th Street Gulfside

Banana Bay Resort & Marina

3.0 star property
7.6 out of 10, Good, (999)
"Great place and staff"
The price is $221
includes taxes & fees
$196 per night
May 11 - May 12
Banana Bay Resort & Marina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Big Pine Key

Meet the local wildlife, splash in the shallows and enjoy the calm of the quieter Keys on this stretch of serene waterfront and wetlands.

Big Pine Key featuring a river or creek, a bay or harbor and general coastal views

Frequently asked questions

Where is the best place for a stay in Big Pine Key?

Barnacle Resort is a favorite property for Expedia customers. This B&B is a short 1-minute walk from Florida Keys Beaches, and it offers free breakfast and free parking. Sunshine Key RV Resort & Marina is another top choice for your stay based on reviews. See all available top hotels, or vacation rentals in Big Pine Key.

What are some of the best vacation home rentals that Big Pine Key has to offer?

Aqua Lodge Rentals At Coconut Cay: This vacation home rental near Big Pine Key is located near the beach and offers an outdoor pool, air-conditioning, and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a full-sized fridge, a stovetop, and a microwave. See all vacation rentals in Big Pine Key.

If I need to cancel my hotel reservation in Big Pine Key, will I receive a refund?

Yes! Most room reservations are fully refundable if cancelled before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If your reservation is non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Big Pine Key.

Where can I learn more about changing or cancelling my trip to Big Pine Key?

For more details about rescheduling or cancelling your trip to Big Pine Key, click here.

What's the best place to stay on a budget in Big Pine Key?

Based on reviews, Old Wooden Bridge Marina is a popular 2.5-star cottage for our travelers looking for an economical choice, and features free WiFi and free parking.

What's the best place to stay for a family vacation in Big Pine Key?

Old Wooden Bridge Marina is a cottage with an outdoor pool and in-room kitchens, and it's a top choice on Expedia for families. Attractions in the area like Island Hoppers Aerial Adventures and Crane Point Museum and Nature Center are also fun for kids of all ages.

What's the best pet-friendly accommodation in Big Pine Key?

Ocean Depth Room Barnacle bed and breakfast Suite is a top guesthouse for people traveling with their pets, and offers in-room balconies for its human guests. Ocean View Room Barnacle bed and breakfast is another option for you and your pet. See more pet-friendly hotel accommodations in Big Pine Key.

Where is the best hotel to stay with easy access to National Key Deer Refuge Visitor Center?

Parmer's Resort is one of the top choices for your stay based on our traveler data, and this property offers a marina and a private beach. It's located 2.1 mi (3.4 km) from National Key Deer Refuge Visitor Center. Another good choice is Little Palm Island Resort & Spa - A Noble House Resort, located 0.7 mi (1.2 km) away.

What about the best place to stay close to No Name Key?

One of the top choices for your stay is Old Wooden Bridge Marina, located 1.5 mi (2.4 km) from No Name Key, and this cottage offers a marina and an outdoor pool.

What's the best hotel to stay near the beach in Big Pine Key?

Barnacle Resort is a top beachfront B&B offering free breakfast and free WiFi, located within a short 1-minute walk of Florida Keys Beaches. Deer Run Bed & Breakfast is another good option to stay near the beach. See more stays near the beach in Big Pine Key.

What are some accommodations with pools in Big Pine Key?

Old Wooden Bridge Resort and Marina: Features free self parking, an outdoor pool, and complimentary wireless internet access. Sunshine Key RV Resort & Marina and Tropical Caribbean Paradise with pool! are a couple of other choices that feature an onsite pool. View all hotels with pools in Big Pine Key.

What is the best spa hotel in Big Pine Key?

Barnacle Bed and Breakfast is a top beach spa hotel with a rooftop terrace. Kick back and relax in the spa tub. Another popular spa hotel in Big Pine Key is Deer Run Bed & Breakfast. See all spa hotels in Big Pine Key.

What is the best hotel near Miami International Airport (MIA)?

Miami International Airport Hotel is a popular 3-star hotel featuring a restaurant and free WiFi. It's located a short 0.1 mi (0.1 km) from Miami Intl. Airport. Other accommodations within close proximity to the airport include Ramada by Wyndham Miami Springs/Miami International Airport and Comfort Suites Miami Airport North.

How is it to stay in Big Pine Key?

Visitors can enjoy all that Big Pine Key has to offer including its beaches. In Big Pine Key, there are 164 hotels and other accommodations to choose from. Find out more about Big Pine Key.

What are the top places to visit in Big Pine Key?

Favorite family attractions include Blue Hole and Big Munson Island. Natural beauty is on display at Calusa Beach, Florida Keys Beaches, and Cook Island. A couple of additional sights to add to your agenda are Bahia Honda State Park and Big Pine Key Flea Market. Check out what more to see and do in Expedia's Big Pine Key guide.

What's the seasonal weather like in Big Pine Key?

The hottest months are usually August and July with an average temp of 84°F, while the coldest months are January and February with an average of 72°F. Average annual precipitation for Big Pine Key is 36 inches.