
Great Plains Vacations from $272
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
Your Great Plains Vacation
Leave the travel planning up to us with a Great Plains vacation package. With everything organized before you leave home, the only thing left for you to do is sit back, relax and experience this destination's culture and beauty. Your trip to Great Plains wouldn't be complete without experiencing some of its most well-known cities, starting with Houston. Two of the top attractions here include NRG Stadium and MD Anderson Cancer Center. Denver should also be on the itineraries of all Great Plains travelers. Visitors to this destination love Union Station and Empower Field at Mile High. Expedia has flights, hotels and everything else you need to help you curate your very own tailored Great Plains vacation today.
The Latest Great Plains Vacation Packages


The LEEF Hotel
Reviewed on Apr 28, 2025

Glendale Hotel
Reviewed on Apr 29, 2025


OYO Hotel and Casino Las Vegas
Reviewed on Apr 30, 2025
Where to stay in Great Plains

Downtown Denver
Dive into this bustling financial and entertainment hub, featuring the 16th Street pedestrian mall, Larimer Square, and the Theatre District. Catch a game at Coors Field or Ball Arena, and explore the neighborhood's vibrant dining scene.
Find the Best Great Plains Vacation Packages
Great Plains Hotel Deals

Reviewed on Apr 29, 2025

Reviewed on Apr 29, 2025

Reviewed on Apr 29, 2025
Discover the most popular places to visit in Great Plains

Mount Rushmore
Explore the great outdoors at Mount Rushmore, a popular spot to commune with nature in Keystone. Discover the area's notable monuments, or seek out its horseback riding.

Union Station
Combining transit, accommodations, shopping, dining, and events, this landmark building in downtown Denver offers history and excitement in the Mile High City.

Mount Rushmore National Memorial
Visit this popular landmark in South Dakota to see firsthand the enormous sculptures of four U.S. presidents carved into a mountain.
What to do in Great Plains
