Los Santos Vacations & Trips from $438

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Your Los Santos Vacation

Embark on a journey full of discovery and excitement with a vacation package to Los Santos. Known for its festivals and so much more, this destination will surprise and delight at every step. A trip to Los Santos wouldn't be complete without spending some time in its best cities, starting with Pedasi. Some of the top attractions here include Iguana Island National Park and Playa El Arenal. Las Tablas is another favorite with Los Santos travelers. Visitors to this exciting city enjoy El Uverito Beach and Playa Las Comadres. Expedia has everything you need for organizing your Los Santos vacation. From flights and accommodations, to rental cars and activities, we're here to help you curate a travel experience like no other.

Top destinations in Los Santos

Mil Polleras Festival! #lifeatexpedia
FlightsFlightsHotelsHotels

Las Tablas

Las Tablas

The Latest Los Santos Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Room in Guest Room - Room in Comfortable Apartment Located on the Beach Very Close to the City

Room in Guest Room - Room in Comfortable Apartment Located on the Beach Very Close to the City

3 out of 5
per person
Jul 6 - Jul 11
found 1 day ago
Roundtrip flight included
Miami (MIA) to Panama City (PTY)
No reviews
Residencia Natural

Residencia Natural

3 out of 5
per person
Jul 20 - Jul 27
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
10/10 Exceptional! (6 reviews)
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Jul 24 - Jul 28
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (863 reviews)
Very nice hotel! Staff is very friendly

Reviewed on Apr 29, 2025

Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
per person
Jul 20 - Jul 27
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.8/10 Exceptional! (56 reviews)
Host was excellent. Great communication and very helpful. The rooms were nice and great value.

Reviewed on Apr 18, 2025

Punta Caracol Acqua Lodge

Punta Caracol Acqua Lodge

3.5 out of 5
Punta Caracol
Save 100% on your flight
per person
Jul 20 - Jul 27
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.6/10 Excellent! (139 reviews)
Good place for relax and enjoy good vacations with the family

Reviewed on Apr 6, 2025

Best Places to Vacation in Los Santos

1. Find your perfect Las Escobas del Venado vacation

Las Escobas del Venado in Los Santos, Panama offers the perfect atmosphere for a beach vacation. With its secluded and pristine beaches, it is an ideal destination for those looking to relax and enjoy nature. The area is also known for its great surfing opportunities, with waves that cater to both beginners and experienced surfers. Visitors can take long walks along the shoreline, bask in the warm sun, and admire breathtaking sunsets. For those seeking a lively atmosphere, there are beach bars where you can sip on refreshing drinks and soak in the vibrant marina scene.

  • Travelers tend to stay 3 days in Las Escobas del Venado

2. Escape to Pedasi with a vacation package

Pedasi in Los Santos, Panama, offers a perfect atmosphere for a beach vacation. With its stunning geographic location and beautiful beaches, it is an ideal destination for relaxation. The locals in Pedasi are known for their friendliness and welcoming nature, making visitors feel right at home. The town also offers a variety of dining options, allowing travelers to indulge in delicious local cuisine. Some popular activities for travelers to enjoy here are vacation packages that include beach activities and exploring the natural beauty of the area. Overall, Pedasi promises a memorable and enjoyable beach vacation experience.

  • The peak season is from January to March
  • The off-peak season is from August to October
  • Travelers tend to stay 3 days in Pedasi

3. Discover Las Tablas with our vacation deals

Las Tablas, located in Los Santos, Panama, is the perfect destination for a beach vacation. With its budget-friendly options and abundance of excursions, visitors can enjoy the stunning sandy beaches and crystal-clear waters. Seafood lovers will delight in the fresh and delicious seafood options available, while adventure enthusiasts can partake in activities like walking and exploring the natural parks. Las Tablas is also a family-friendly destination, offering a range of activities suitable for all ages. Whether you're looking for relaxation or adventure, Las Tablas has it all.

  • The peak season is from December to February
  • The off-peak season is from April to June
  • Travelers tend to stay 2 days in Las Tablas

4. Enjoy Cambutal with a travel package

Cambutal, located in Los Santos, Panama, offers a serene and picturesque beach vacation experience. Nestled within stunning geographic affinities, this coastal destination is perfect for relaxation and rejuvenation. With its pristine sandy beaches and crystal-clear turquoise waters, Cambutal is ideal for sunbathing, swimming, and water sports. The local atmosphere is laid-back and welcoming, allowing travelers to unwind and immerse themselves in the natural beauty of the surroundings. Whether you choose to explore the lush rainforests nearby or simply bask in the sun, Cambutal provides an idyllic beach getaway for travelers seeking tranquility and natural splendor.

  • Travelers tend to stay 4 days in Cambutal

6. Plan your dream getaway to Guanico Abajo

Guanico Abajo in Los Santos, Panama, offers a delightful beach vacation experience. With its beautiful coastline and picturesque surroundings, it is the perfect destination for relaxation and fun in the sun. The local atmosphere is laid-back and friendly, allowing travelers to immerse themselves in the tranquil vibes of this coastal town. Whether you want to lounge on the sandy beaches, go swimming in the crystal-clear waters, or explore the nearby nature reserves, Guanico Abajo has something for everyone. Experience the beauty and charm of this beach paradise during your vacation stay.

  • Travelers tend to stay 3 days in Guanico Abajo

5. Explore Canas with a vacation package

Canas, located in the beautiful region of Los Santos, Panama, offers an idyllic beach vacation experience. With its pristine white sand beaches and crystal-clear turquoise waters, it's the perfect destination for relaxation and rejuvenation. The local atmosphere is laid-back and welcoming, with friendly locals and a peaceful ambiance. Whether you want to soak up the sun, enjoy water activities like snorkeling and swimming, or simply unwind with a book by the shore, Canas has it all. Immerse yourself in the local culture, indulge in delicious seafood, and savor breathtaking sunsets over the Pacific Ocean for an unforgettable beach vacation.

  • Travelers tend to stay 2 days in Canas

Find the Best Los Santos Vacation Packages

Best months to visit Los Santos

Looking for the best time to visit Los Santos? Our table will help you. Los Santos boasts a year-round average temperature of 78.6°F, reaching a peak of 80.4°F in April, its warmest month, and dropping to an average low of 77.2°F in November, the coolest month. The annual rainfall averages 200.2mm, with October experiencing the heaviest showers, while February is the driest month.

Monthcalendar iconTemperature (Fahrenheit)temperature iconRainfallrain iconCloud coveragecloud icon
January78.1No Rain (Dry)Mostly Sunny
February78.8No Rain (Dry)Sunny
March79.5No Rain (Dry)Mostly Sunny
April80.4Light RainMostly Sunny
May79.9Moderate RainMostly Cloudy
June79.0Frequent RainMostly Cloudy
July78.6Moderate RainMostly Cloudy
August78.6Frequent RainMostly Cloudy
September78.4Frequent RainMostly Cloudy
October77.5Frequent RainMostly Cloudy
November77.2Frequent RainMostly Cloudy
December77.5Light RainMostly Sunny

How to save money on a vacation to Los Santos

  • Combine your flights with hotels or car rentals to save money, especially in Los Santos.
  • Take advantage of Expedia's OneKey program to collect points and save money on your trip to Los Santos.
  • Utilize the helpful search filters on Expedia to find the perfect accommodation within your price range.
  • Consider traveling during the off-peak season in Los Santos, which is from December to February, for better deals.
  • Use the search filter for price limits on Expedia to find a package deal that suits your budget.
  • Discover the best vacation experience for you by using the travel experience filter on Expedia, whether it's a family, romantic, or adventurous getaway.

Los Santos Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)
Top Sights
Venao Beach, El Uverito Beach and Playa El Toro

Los Santos Hotel Deals

Hotel Posada Destiladeros
Hotel Posada Destiladeros
3 out of 5
Calle principal Los Destiladeros, Los Destiladeros Pedasi, Punta Mala, Provincia de los Santos
Fully refundableReserve now, pay when you stay
The price is $94 per night from May 1 to May 2
$94
includes taxes & fees
$85 per night
May 1 - May 2
9/10 Wonderful! (32 reviews)
"Hotel Posada Destiladeros is an undiscovered gem on the Azuela Peninsula! I enjoyed a rejuvenating 3 day stay in the Vietnam room, overlooking deserted Ocean beaches. A professional chef prepared meals with ingredients sourced locally - including fish and seafood. I watched the sunrise and sunset ..."

Reviewed on Apr 3, 2025

Hotel Posada Destiladeros
Villa Marina Lodge & Condos
Villa Marina Lodge & Condos
3.5 out of 5
Playa Venao, Las Escobas del Venado, Los Santos
Fully refundableReserve now, pay when you stay
The price is $210 per night from May 14 to May 15
$210
includes taxes & fees
$191 per night
May 14 - May 15
Beautiful property and quiet location
"Gorgeous old school resort"

Reviewed on Mar 25, 2025

Villa Marina Lodge & Condos
Hotel Presidente
Hotel Presidente
3.5 out of 5
Calle Moises Espino, y Calle Pablo Arosemena, Las Tablas
The price is $88 per night from May 5 to May 6
$88
includes taxes & fees
$80 per night
May 5 - May 6
9/10 Wonderful! (98 reviews)
"Staff was great. I was practicing my Spanish and some were practicing English so we had fun each evening on the roof having dinner and drinks."

Reviewed on Mar 25, 2025

Hotel Presidente
See all 365 properties in Los Santos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Kid Friendly Vacations

Kid Friendly Vacations

Frequently asked questions

How much does a Los Santos vacation package cost?
Our Los Santos packages, which begin from just $438, are an awesome way to save precious money. Select your favorite hotels, flights and more to create your ideal trip.
How do I get a cheap travel package to Los Santos?
Combine your hotel and flight bookings, throw in extras such as activities or a rental car, and save with a Los Santos vacation package. You won’t just land big discounts on your adventure — you’ll have a world of choice within your reach too. When you book with Expedia, you can choose from more than 550 air carriers and 1,000,000 properties globally. Your next big adventure starts right here, right now!
What are the top hotels in Los Santos?
For properties in Las Escobas del Venado with cozy beds and friendly service, you can’t beat Hotel Presidente and Villa Marina Lodge And Condos. If you’re swinging by Pedasi as well, you’ll get a good night’s sleep at Hotel Punta Franca or Selina Playa Venao - Hostel.
How far in advance should I book my Los Santos vacation?
While prices change frequently, we generally recommend reserving your seat as soon as possible. Most international airfares can be compared on Expedia up to a year in advance. If circumstances have left you booking last minute, you might still get lucky. Cheap tickets to Los Santos sometimes appear only weeks before departure.
What does an Expedia Los Santos travel package include?
Flights, hotels and a reliable car for all your fun road trip adventures. Simply select your preferred bundle and get access to great discounts. Once you’ve made your booking, add on some experiences and tours and watch your savings pile up. When it comes to planning your Los Santos trip, you’re the boss!
What should I know before booking a Los Santos travel package?
When you book your hotels, flights and car rentals together, you’ll pick up awesome discounts. Whether you’re planning an island getaway in a villa or would rather stay in a fancy hotel in the city, Expedia can help make it happen.
Can I choose my airline with a Los Santos Expedia vacation package?
With a vacation package, you’re the one in charge. Whether you’d like to fly to Los Santos in first class or coach, simply select from the available airline options. Expedia has access to over 550 airline partners around the world.
Does Expedia offer Book Now, Pay Later Los Santos vacation packages?
Thanks to our partnership with online lender Affirm, vacationers booking via Expedia can now pay off their journey in easy installments that won’t hurt your savings. Book Now, Pay Later and begin your dream vacation today!
If I'm not able to travel, can I cancel my Los Santos vacation package?
Your situation can change suddenly, so yes, you can. You may be able to amend or cancel your Los Santos vacation package at no cost within 24 hours of booking. For bookings made more than 24 hours ago, you can still cancel or make changes, but your car rental company, airline or hotel may impose a charge. Want more information? Look up our Customer Service Portal. We’re here to help make sure your getaway goes off without a hitch.

Discover the most popular places to visit in Los Santos

Playa El Arenal

Playa El Arenal

4/5(7 reviews)

If a restful vacation is part of your travel plans, Playa El Arenal might be the perfect place to seek out during your trip to Pedasí.

Playa El Arenal
Selina Hostels at Playa Venao The hostel is new and not finished yet, but it has a great design, is located directly at the beach and the staff is really cool. A con is that there is only one shop which has basically nothing and is really expensive; so you either have to bring your food or eat at the bar in the hostel. The beach itself is good for surfers, but you can also enjoy the waves without a board. There are only two (or maybe three; nobody knows) buses from Pedasí to Playa Venao: once in the morning (I think at 7) and once at 12 o'clock. It takes around 1.5 hours. Keep your eyes open and when you see the sign of the hostel, shout

Los Destiladeros Beach

4/5(8 reviews)

If a restful vacation is part of your travel plans, Los Destiladeros Beach might be the perfect place to seek out during your trip to Punta Mala.

Los Destiladeros Beach
Sunset at Sansara

Los Buzos Beach

5/5(1 review)

If a restful vacation is part of your travel plans, Los Buzos Beach might be the perfect place to seek out during your trip to Cambutal.

Los Buzos Beach
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.