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Find hotels near Mayo Clinic Florida, Jacksonville from $129

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Apr 28 - Apr 29
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Apr 29 - Apr 30
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May 2 - May 4
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May 9 - May 11

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Compare 1,857 hotels close to Mayo Clinic Florida with room rates, reviews, and availability. Most hotels are fully refundable.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Reception

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property
9.4 out of 10, Exceptional, (370)
"Great place highly recommend "
The price is $199
includes taxes & fees
$175 per night
May 4 - May 5
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Terrace/patio

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

2.5 star property
9.0 out of 10, Wonderful, (1002)
"Good hotel to stay"
The price is $134
includes taxes & fees
$118 per night
May 11 - May 12
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Suite, 1 King Bed (Additional Living Area) | Golf view

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

2.5 star property
8.4 out of 10, Very Good, (1007)
"I loved the renovation in the breakfast area. "
The price is $147
includes taxes & fees
$130 per night
May 11 - May 12
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Terrace/patio

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

3.0 star property
8.4 out of 10, Very Good, (714)
"Close to mayo"
The price is $183
includes taxes & fees
$161 per night
May 10 - May 11
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Element Jacksonville Beach
Lobby

Element Jacksonville Beach

3.0 star property
9.6 out of 10, Exceptional, (465)
"Very clean and good location "
The price is $163
includes taxes & fees
$144 per night
May 11 - May 12
Element Jacksonville Beach
Ponte Vedra Inn & Club
Reception

Ponte Vedra Inn & Club

5.0 star property
9.4 out of 10, Exceptional, (783)
"Always enjoy staying here."
The price is $474
includes taxes & fees
$428 per night
Apr 30 - May 1
Ponte Vedra Inn & Club
The Hotel Palms
Standard Room, 2 Queen Beds, Non Smoking | Down comforters, minibar, iron/ironing board, WiFi

The Hotel Palms

3.5 star property
9.6 out of 10, Exceptional, (284)
"Relaxing and calm "
The price is $244
includes taxes & fees
$215 per night
Apr 29 - Apr 30
The Hotel Palms
The Lodge and Club at Ponte Vedra Beach
Beach/ocean view

The Lodge and Club at Ponte Vedra Beach

5.0 star property
9.4 out of 10, Exceptional, (660)
"Great location and amazing service!"
The price is $585
includes taxes & fees
$528 per night
May 11 - May 12
The Lodge and Club at Ponte Vedra Beach
AC Hotel Jacksonville St Johns Town Center
Lounge

AC Hotel Jacksonville St Johns Town Center

2.5 star property
9.4 out of 10, Exceptional, (98)
"Wonderfull hotel"
The price is $215
includes taxes & fees
$189 per night
May 22 - May 23
AC Hotel Jacksonville St Johns Town Center
Salt Air Inn & Suites
BBQ/picnic area

Salt Air Inn & Suites

2.5 star property
9.8 out of 10, Exceptional, (317)
"Cute place, super convenient to Beaches Town Center. "
The price is $183
includes taxes & fees
$161 per night
May 4 - May 5
Salt Air Inn & Suites
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Exterior

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

2.5 star property
9.4 out of 10, Exceptional, (1002)
"The staff, property and location were amazing!"
The price is $135
includes taxes & fees
$119 per night
May 4 - May 5
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Residence Inn by Marriott Jacksonville South/Bartram Park
Fireplace

Residence Inn by Marriott Jacksonville South/Bartram Park

3.0 star property
9.4 out of 10, Exceptional, (560)
"Great property with even better customer service!"
The price is $142
includes taxes & fees
$125 per night
May 4 - May 5
Residence Inn by Marriott Jacksonville South/Bartram Park
Hampton Inn & Suites Jacksonville Deerwood Park
Studio, 2 Queen Beds, Accessible, Non Smoking | Living area | 43-inch LCD TV with satellite channels, TV

Hampton Inn & Suites Jacksonville Deerwood Park

2.5 star property
9.2 out of 10, Wonderful, (1004)
"This was our 3rd stay— great, central location: 5 minutes to our daughter, our Jacksonville church, easy access to highways, riverfront & beaches. Rooms always ready, good breakfast & pool was clean & nice temperature for April."
The price is $129
includes taxes & fees
$114 per night
May 18 - May 19
Hampton Inn & Suites Jacksonville Deerwood Park
Hyatt Place Jacksonville / St. Johns Town Center
Sports facility

Hyatt Place Jacksonville / St. Johns Town Center

3.0 star property
9.2 out of 10, Wonderful, (1006)
"Great place! Will be staying again! "
The price is $144
includes taxes & fees
$127 per night
May 11 - May 12
Hyatt Place Jacksonville / St. Johns Town Center
Candlewood Suites Jacksonville - Mayport by IHG
Studio Suite, 2 Queen Beds | Down comforters, desk, laptop workspace, blackout drapes

Candlewood Suites Jacksonville - Mayport by IHG

2.5 star property
9.0 out of 10, Wonderful, (219)
"Nice place, nice staff."
The price is $139
includes taxes & fees
$123 per night
May 1 - May 2
Candlewood Suites Jacksonville - Mayport by IHG
Home2 Suites by Hilton Jacksonville-South/St. Johns Town Ctr
Exterior

Home2 Suites by Hilton Jacksonville-South/St. Johns Town Ctr

3.0 star property
8.8 out of 10, Excellent, (277)
"Wonderful stay."
The price is $157
includes taxes & fees
$138 per night
May 4 - May 5
Home2 Suites by Hilton Jacksonville-South/St. Johns Town Ctr
Holiday Inn Express Jacksonville South Bartram Prk by IHG
Interior entrance

Holiday Inn Express Jacksonville South Bartram Prk by IHG

2.5 star property
9.2 out of 10, Wonderful, (1018)
"Great place to stay."
The price is $139
includes taxes & fees
$122 per night
May 4 - May 5
Holiday Inn Express Jacksonville South Bartram Prk by IHG
Hotel Indigo Jacksonville-Deerwood Park by IHG
Exterior

Hotel Indigo Jacksonville-Deerwood Park by IHG

3.5 star property
9.2 out of 10, Wonderful, (1005)
"The bathroom was super nice and very clean! Room was spacious and staff very friendly!"
The price is $149
includes taxes & fees
$131 per night
May 3 - May 4
Hotel Indigo Jacksonville-Deerwood Park by IHG
Holiday Inn Express Jacksonville Beach by IHG
Standard Room, 2 Queen Beds, Accessible (Accessible Tub) | In-room safe, desk, laptop workspace, blackout drapes

Holiday Inn Express Jacksonville Beach by IHG

2.5 star property
9.2 out of 10, Wonderful, (1006)
"Nice hotel, clean, great breakfast & super attentive, friendly staff!"
The price is $149
includes taxes & fees
$131 per night
May 14 - May 15
Holiday Inn Express Jacksonville Beach by IHG
Candlewood Suites Jacksonville East Merril Road by IHG
Exterior

Candlewood Suites Jacksonville East Merril Road by IHG

2.5 star property
8.4 out of 10, Very Good, (517)
"Just stayed 1 night while passing through but hotel was very clean and Elena at the front desk was very friendly and kind. "
The price is $159
includes taxes & fees
$140 per night
May 11 - May 12
Candlewood Suites Jacksonville East Merril Road by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's the area like around Mayo Clinic Florida?

Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 33 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic Florida?

Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Another good choice is Residence Inn By Marriott Jacksonville - Mayo Clinic Area, located just 0.7 mi (1.1 km) away.

How many hotels will I find near Mayo Clinic Florida?

Expedia has 33 hotels and other accommodations within a mile from Mayo Clinic Florida.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.

What can I see and do near Mayo Clinic Florida?

You can enjoy live performances at Players by the Sea and Wilson Center For the Arts. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.