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Compare Santa Ana Luxury Hotels room rates, reviews, and availability. Most hotels are fully refundable.

MainStay Suites John Wayne Airport by Choice Hotels
MainStay Suites John Wayne Airport by Choice Hotels
8.0 out of 10, Very Good, (1105)
The price is $104
includes taxes & fees
$92 per night
May 7 - May 8

Best Western Plus Orange County Airport North
Best Western Plus Orange County Airport North
8.6 out of 10, Excellent, (1557)
The price is $127
includes taxes & fees
$112 per night
May 4 - May 5

Courtyard by Marriott Santa Ana Orange County
Courtyard by Marriott Santa Ana Orange County
8.6 out of 10, Excellent, (1000)
The price is $117
includes taxes & fees
$103 per night
May 11 - May 12

La Quinta Inn & Suites by Wyndham Orange County Airport
La Quinta Inn & Suites by Wyndham Orange County Airport
7.6 out of 10, Good, (1829)
The price is $112
includes taxes & fees
$99 per night
May 5 - May 6

Motel 6 Santa Ana, CA
Motel 6 Santa Ana, CA
7.2 out of 10, Good, (1000)
The price is $82
includes taxes & fees
$73 per night
May 4 - May 5

Express Inn
Express Inn
7.2 out of 10, Good, (1000)

Courtyard by Marriott Costa Mesa South Coast Metro
Courtyard by Marriott Costa Mesa South Coast Metro
8.6 out of 10, Excellent, (1000)
The price is $137
includes taxes & fees
$121 per night
May 11 - May 12

Embassy Suites by Hilton Santa Ana Orange County Airport
Embassy Suites by Hilton Santa Ana Orange County Airport
6.2 out of 10, (1553)
The price is $139
includes taxes & fees
$122 per night
May 11 - May 12
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Santa Ana
Find out more about Santa Ana
How to find luxury hotels in Santa Ana on Expedia
Finding some of the best Santa Ana luxury hotels is a breeze on Expedia thanks to the wide selections of properties available and easy-to-use search wizard. Select your travel dates and, within seconds, it'll show you some of the best luxury hotels in Santa Ana. You can then customize the results using the search filters, such as “star rating”. 5-star hotels in Santa Ana are renowned for their exceptional hospitality that'll make you feel like royalty. There are also top-rated 4-star hotels in Santa Ana that are worth adding to your wish list.
Expedia's range of high-end properties will place you in some of Santa Ana most upscale areas. The “popular locations” and “neighborhood” search filter let you pinpoint hotels in the most exclusive parts of town. If you're planning on a dip in the pool or chilling out with a glass of bubbly in the hot tub, the amenities filters are especially helpful. Once you've found your ideal Santa Ana luxury hotel, you can book a room in just a few easy clicks.
Plan your Santa Ana luxury stay
When weighing up your options for your getaway, it's a good idea to think about what kind of room you'd like to stay in. From sprawling executive suites to state-of-the-art penthouse rooms, you'll find it all on Expedia. Keep an eye out for the size of the room, as well as the type of bedding and views it has. All this information, as well as the cancellation policy, is clearly displayed on Expedia. Luxury hotels with breakfast included in Santa Ana are a popular option where you can, for example, expect artisan breads, gourmet egg dishes, and the finest coffee. Use the “breakfast included” filter to pin down these properties.
Some of the most popular luxurious hotels in Santa Ana boast indulgent spas and wellness centers. Enjoy a restorative facial, pamper your senses with a therapeutic massage, and rejuvenate body and mind with holistic treatments. Be sure to select the “spa” search filter on Expedia to view these types of properties. Many upscale hotels offer concierge services and curated local experiences, allowing you to uncover Santa Ana's hidden gems and get off the beaten path.
You'll also want to consider the dining options on offer at different Santa Ana luxury hotels. The most prestigious properties typically boast opulent restaurants with spectacular views where you can dine on exquisite cuisine. A glass of champagne or after-dinner cocktails are a delightful treat while on vacation, so consider choosing somewhere with an on-site bar. The “bar” and “restaurant” search filters can help locate these.
Why plan your Santa Ana luxury stay on Expedia
From prestigious international brands to high-end local boutiques, you'll find a wide selection of Santa Ana luxury hotels on Expedia. The varied search filters give you total control over your search, making it a breeze to find your ideal place to stay. Whether you're seeking a personalized concierge service that caters to your every whim or chic design and elegant interiors, Expedia's detailed hotel descriptions mean you'll know exactly what to expect when you arrive.
The most upscale stays in Santa Ana in 2025 tend to get booked up in advance. Fortunately, many properties on Expedia allow for free cancellation, so might be able to book your first choice of hotel even if your plans aren't 100% certain. Make sure to read the terms and conditions before booking.
Recent reviews of Santa Ana hotels
Recent reviews of Santa Ana hotels

DoubleTree Suites by Hilton Anaheim Rsrt - Conv Cntr
5/5 Excellent
"Great service"
A verified traveler stayed at DoubleTree Suites by Hilton Anaheim Rsrt - Conv Cntr
Posted 12 hours ago
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Explore a world of travel with Expedia
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