Find hotels near UCSF Mission Bay, San Francisco from $140

    calendar shield illustration
    Change your mind
    Book hotels with free cancellation
    one key illustration
    Treat yourself
    Save instantly and earn perks with One Key
    bed illustration
    Be picky
    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 3,709 hotels close to UCSF Mission Bay with room rates, reviews, and availability. Most hotels are fully refundable.

LUMA Hotel San Francisco

4.0 star property
9.6 out of 10, Exceptional, (2013)
"Great place to stay "
The price is $229
includes taxes & fees
$195 per night
May 30 - May 31
LUMA Hotel San Francisco

The St. Regis San Francisco

5.0 star property
9.4 out of 10, Exceptional, (659)
"Top notch in every aspect of hospitality "
The price is $478
includes taxes & fees
$406 per night
May 23 - May 24
The St. Regis San Francisco

Canopy by Hilton San Francisco SoMa

4.0 star property
9.0 out of 10, Wonderful, (832)
"Our stay was great!!! Would stay there again"
The price is $205
includes taxes & fees
$174 per night
May 25 - May 26
Canopy by Hilton San Francisco SoMa

citizenM San Francisco Union Square

4.0 star property
9.6 out of 10, Exceptional, (1233)
"Was a nice stay"
The price is $175
includes taxes & fees
$149 per night
May 11 - May 12
citizenM San Francisco Union Square

Hyatt Regency San Francisco Downtown SOMA

4.0 star property
9.2 out of 10, Wonderful, (1458)
"Would stay here again "
The price is $196
includes taxes & fees
$167 per night
May 9 - May 10
Hyatt Regency San Francisco Downtown SOMA

Hotel Nikko San Francisco

4.5 star property
9.4 out of 10, Exceptional, (2322)
"Nice pool & restaurants, great location "
The price is $220
includes taxes & fees
$187 per night
May 3 - May 4
Hotel Nikko San Francisco

Four Seasons Hotel San Francisco

5.0 star property
9.4 out of 10, Exceptional, (1002)
"Everything about the stay was just what we needed!"
The price is $488
includes taxes & fees
$415 per night
May 9 - May 10
Four Seasons Hotel San Francisco

Chancellor Hotel on Union Square

3.5 star property
9.4 out of 10, Exceptional, (2697)
"Friendly staff, quiet comfortable room "
The price is $143
includes taxes & fees
$122 per night
May 29 - May 30
Chancellor Hotel on Union Square

Inn San Francisco

2.5 star property
9.6 out of 10, Exceptional, (520)
"Breakfast"
The price is $283
includes taxes & fees
$243 per night
May 7 - May 8
Inn San Francisco

The Clancy, Autograph Collection

4.0 star property
9.2 out of 10, Wonderful, (1002)
"Overall a great stay."
The price is $220
includes taxes & fees
$187 per night
May 30 - May 31
The Clancy, Autograph Collection

Inn At Union Square

3.5 star property
9.4 out of 10, Exceptional, (1001)
"Great spot def recommend!"
The price is $160
includes taxes & fees
$139 per night
May 25 - May 26
Inn At Union Square

Orchard Garden Hotel

4.0 star property
9.6 out of 10, Exceptional, (1001)
"Very nice hotel in great location."
The price is $175
includes taxes & fees
$149 per night
May 4 - May 5
Orchard Garden Hotel

W San Francisco

4.5 star property
8.8 out of 10, Excellent, (1001)
"The rooms are nice and staff is friendly. "
The price is $224
includes taxes & fees
$191 per night
May 9 - May 10
W San Francisco

San Francisco Marriott Marquis

4.0 star property
8.8 out of 10, Excellent, (1291)
"Great hotel to stay "
The price is $203
includes taxes & fees
$172 per night
May 30 - May 31
San Francisco Marriott Marquis

Palace Hotel, a Luxury Collection Hotel, San Francisco

5.0 star property
9.0 out of 10, Wonderful, (1002)
"Always a wonderful stay"
The price is $310
includes taxes & fees
$263 per night
May 2 - May 3
Palace Hotel, a Luxury Collection Hotel, San Francisco

Holiday Inn Express San Francisco Union Square by IHG

2.5 star property
8.6 out of 10, Excellent, (553)
"i recommend this Hotel to my friends"
The price is $140
includes taxes & fees
$119 per night
May 26 - May 27
Holiday Inn Express San Francisco Union Square by IHG

Hotel Zelos San Francisco

4.0 star property
9.0 out of 10, Wonderful, (1000)
"Great location, and very nice staff!"
The price is $207
includes taxes & fees
$176 per night
May 9 - May 10
Hotel Zelos San Francisco

The Marker Union Square San Francisco

4.0 star property
8.8 out of 10, Excellent, (1001)
"Beautiful hotel! Food and service great in the restaurant."
The price is $178
includes taxes & fees
$151 per night
May 21 - May 22
The Marker Union Square San Francisco

Axiom Hotel

4.0 star property
8.6 out of 10, Excellent, (1000)
"Steps away from Powell street station. Right in union square. Very convenient "
The price is $152
includes taxes & fees
$129 per night
May 9 - May 10
Axiom Hotel

Beacon Grand, A Union Square Hotel

4.0 star property
9.2 out of 10, Wonderful, (1427)
"great stay and good"
The price is $222
includes taxes & fees
$189 per night
May 31 - Jun 1
Beacon Grand, A Union Square Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Don't see what you're looking for?
See all available properties in UCSF Mission Bay
Save an average of 15% on thousands of hotels when you're signed in

Frequently asked questions

What's the area like around UCSF Mission Bay?

UCSF Mission Bay is located in a vibrant area of San Francisco known for its top museums and stunning architecture. If you're looking for a convenient place to stay, check out the 83 hotels and other accommodations you'll find within a mile.

Where is the best place to stay near UCSF Mission Bay?

LUMA Hotel San Francisco is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a fitness center. It's located just a short 0.4 mi (0.7 km) from UCSF Mission Bay. Other good choices within a short distance include Hyatt Place San Francisco Downtown and Hotel VIA.

How many hotels are there close to UCSF Mission Bay?

Expedia has 83 hotels and other accommodations within a mile from UCSF Mission Bay.

If I need to cancel the hotel reservation for my stay near UCSF Mission Bay, will I receive a refund?

Yes! You'll find that most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of your booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to get the best options available near UCSF Mission Bay.

Where can I learn more about changing or cancelling my trip in the area near UCSF Mission Bay?

For more information about rescheduling or cancelling your stay near UCSF Mission Bay, go to https://www.expedia.com/service/.

What can I see and do near UCSF Mission Bay?

Study the collections at San Francisco Museum of Modern Art, Asian Art Museum of San Francisco, or Market Street Railway Museum. Sights like Alcatraz Island, San Francisco Mint, and 450 Sutter Building are landmarks to visit in the area. You can check out the local talent at Golden Gate Theatre, Warfield Theatre, and Orpheum Theatre.

How can I get to UCSF Mission Bay?

With so many transportation options, seeing the area around UCSF Mission Bay is easy. Take advantage of metro transit at Market St & 5th St Stop, Market St & Taylor St Stop, and Powell St & Market St Stop. If you're taking a train into town, San Francisco Station is the closest station to Downtown San Francisco.